The study assessed the effect of GALS project on women empowerment in rural areas in Kamonyi and Muhanga Districts, Rwanda. Specific objectives were to evaluate the GALS project activities and services to the farmer’s women in Kamonyi and Muhanga Districts; to analyze the relationship between GALS activities and farmer’s women empowerment in Rural areas of Kamonyi and Muhanga Districts; and to examine the critical success indicators of farmer’s women empowerment before and after joining Gender Action Learning System (GALS) program. Target population was 5,014 farmers (3219 women and 1795 men). This study used purposive and stratified sampling techniques. Data collection techniques and tools were questionnaires, and documentary review. Method of data analysis were descriptive statistical method and cumulative percentages of data. The findings displayed that GALS program activities represented by livelihood planning, adaptation of the GALS “mother” manual, capacity-building and gender training, Agriculture extension service provision which has contributed R=0.930a of the variation in success of empowering farmer’s women as explained by r2 of 0.864