The general objective was the effect of project management practices on performance of Muhanga Road-karongi construction project by Horizon Ltd, Rwanda.The study adopted descriptive research design. To collect primary data the respondents answered questions administered to them through questionnaires. Unit of observation consisted of the Project manager ,Human Resource office manager, siteforemen, Draftsmen, Architecture, Quantity surveyors, Engineers, Technical staff.The target population for this study was 600 project employees and the study was undertake sample size of 240 respondents.The findings revealed that M&E planning, stakeholder involvement in M&E, and M&E implementation had a notable impact on project performance. The overall mean scores for project planning, project communication,  project resource management  and project monitorig ad evaluation  were 4.51, 4.48,4.29,4.79 and 4.35, respectively, while the overall mean for project performance was 4.64, indicating a positive performance trend. According to the results, the correlation between project planning, Project communication, Project resource management, and project monitoring and evaluation was 0.950, 0.891,0.880 and 0.899 respectively.The results present the variables of Effect of project management practices;project planning was statistically significant with p value=0.000b, the Project communication was statistically significant with p value=0.022b, and the Project resource management was not statistically significant with p value=0.809b. and project project monitoring and evaluation was not statistically significant with p value=0.051b.Ministry of Infrastructure (MININFRA), engage citizens actively in the construction sector. This can be achieved through awareness campaigns, training programs, and collaborative initiatives that empower individuals to participate in this industry, ultimately leading to enhanced employment opportunities and financial benefits for the community.