Gender based violence contrary to women is linked to gender inequalities, and gender norms according to which the female and the feminine is related with weakness, inferiority and victimization. The problem of this study was to find out how do socio-economic and health impacts of violence against women and children in Kigali City. Methodology of this study used target population of 18 employees from Isange One Stop Center who deal day to day with GBV victims. With universal sampling technique, the sample size was 18 respondents. Data collection instruments were questionnaire, and documentary instruments. Data analysis done using SPSS and descriptive Statistic method. The findings were presented in accordance with the research objectives where there are different health impact of women and children exposed to gender-based violence in Kigali city such as vaginal bleeding or pelvic pain as confirmed by 83.3%; and unwanted pregnancy on 50.0%. There are various socio-economic impacts of women and children victims who affected by gender violence indicated by loss of income; and loss of consumption/welfare as confirmed by 50.0%; out-of-pocket expenditure accessing health/legal services was on 66.7%; and loss of quality of life confirmed by 83.3%. The strategies and actions to counterfeit violence against women and children in Rwanda are promoting gender equality as a critical part of violence prevention and school initiatives are well placed to prevent violence against women as confirmed by 66.7%. As recommendation, we should have to continue awareness raising campaign on different forms of GBV focusing on the least know none, including psychological and emotional violence; and promoting gender equality is a critical part of violence prevention.